Article
Bone metabolism markers predict increase in bone mass, height and sitting height during puberty depending on the VDR Fok1 genotype.
Clinical endocrinology - 1 Jun 2006
Terpstra L, Knol D L, Van Coeverden S C, Delemarre-van de Waal H A
Abstract excerpt
OBJECTIVES: Longitudinal growth and bone mass accumulation are two important phenomena during puberty, resulting in attainment of peak bone mass (PBM) and final height. They are thought to be under strong genetic control, with the vitamin D receptor (VDR) gene being among the candidate genes. Bone metabolism markers are reported to be good predictors of longitudinal growth and bone mass increase. The purpose of...
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