Mutations in MODY genes are not common cause of early-onset type 2 diabetes in Mexican families.

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Mutations in MODY genes are not common cause of early-onset type 2 diabetes in Mexican families.

JOP : Journal of the pancreas - 10 May 2005

Domínguez-López Aarón, Miliar-García Angel, Segura-Kato Yayoi X, Riba Laura, Esparza-López Riba, Ramírez-Jiménez Salvador, Rodríguez-Torres Maribel, Canizales-Quinteros Samuel, Cabrera-Vásquez Siraam, Fragoso-Ontiveros Verónica, Aguilar-Salinas Carlos A, Altamirano-Bustamante Nelly, Calzada-León Raúl, Robles-Valdés Carlos, Bravo-Ríos Luz E, Tusié-Luna Maria Teresa

Abstract excerpt

CONTEXT: Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes mellitus characterized by autosomal dominant inheritance, early age of onset and a primary insulin secretion defect. Certain MODY gene sequence variants may be involved in polygenic forms of type 2 diabetes. OBJECTIVE: We assessed the contribution of MODY genes to the etiology of type 2 early-onset diabetes in 23 Mexican...

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PMID: 15883474

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