Article
Nine novel mutations in maturity-onset diabetes of the young (MODY) candidate genes in 22 Spanish families.
The Journal of clinical endocrinology and metabolism - 1 Jun 2002
Barrio R, Bellanné-Chantelot C, Moreno J C, Morel V, Calle H, Alonso M, Mustieles C
Abstract excerpt
The aims of this study were to estimate the prevalence of major maturity-onset diabetes of the young (MODY) subtypes in Spanish MODY families and to analyze genotype-phenotype correlations. Twenty-two unrelated pediatric MODY patients and 97 relatives were screened for mutations in the coding region of the glucokinase (GCK), hepatic nuclear factor- HNF-1alpha and HNF4alpha genes using PCR-single strand...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.