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Article

ACT-5 is an essential Caenorhabditis elegans actin required for intestinal microvilli formation.

Molecular biology of the cell - 1 Jul 2005

MacQueen A J, Baggett J J, Perumov N, Bauer R A, Januszewski T, Schriefer L, Waddle J A

Abstract excerpt

Investigation of Caenorhabditis elegans act-5 gene function revealed that intestinal microvillus formation requires a specific actin isoform. ACT-5 is the most diverged of the five C. elegans actins, sharing only 93% identity with the other four. Green fluorescent protein reporter and immunofluorescence analysis indicated that act-5 gene expression is limited to microvillus-containing cells within the intestine...

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Identifiers

PMID: 15872090
DOI: 10.1091/mbc.e04-12-1061
PMCID: PMC1165408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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