Article
Targeting the photoreceptor cilium for the treatment of retinal diseases.
Acta pharmacologica Sinica - 1 Nov 2020
Ran Jie, Zhou Jun
Abstract excerpt
Photoreceptors, as polarised sensory neurons, are essential for light sensation and phototransduction, which are highly dependent on the photoreceptor cilium. Structural defects and/or dysfunction of the photoreceptor cilium caused by mutations in photoreceptor-specific genes or common ciliary genes can lead to retinal diseases, including syndromic and nonsyndromic diseases. In this review, we describe the...
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