Article
Variability of familial risk of Alzheimer disease across the late life span.
Archives of general psychiatry - 1 May 2005
Silverman Jeremy M, Ciresi Gregory, Smith Christopher J, Marin Deborah B, Schnaider-Beeri Michal
Abstract excerpt
CONTEXT: The role of genetic factors in Alzheimer disease (AD) varies across the late life span, complicating efforts to quantify the risk of AD for relatives of probands with AD. OBJECTIVES: To visualize the changing levels of familial risk according to proband onset age and the age of the at-risk relative and to determine the familiality of age at onset in AD. DESIGN: A retrospective, informant-based family...
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