Article
A new monoclonal antibody which binds to the cytoplasm of large cell lymphomas.
Hematological oncology - 1 Jan 2000
Nakamura N, Suzuki S, Ono N, Tominaga K, Hojo H, Abe M, Wakasa H
Abstract excerpt
We reported a new monoclonal antibody, designated FUB-1, reacting with normal and neoplastic large lymphoid cells. FUB-1 was produced using a Burkitt's lymphoma cell line (HBL-5) as an immunogen. Its immunoglobulin subtype was IgM. The determinant was not on the surface but in the cytoplasm. Western blotting analysis revealed that the molecular weight of the antigen was 52,000 dalton. In the normal lymphoid...
Topics
- Antibodies, Monoclonal
- Burkitt Lymphoma
- Genotype
- Humans
- Immunoglobulin G
- Immunophenotyping
- Karyotyping
- Lymphoma, Large B-Cell, Diffuse
- Tumor Cells, Cultured