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Article

In vivo binding of mouse IgG via polyreactive surface IgM abrogates progressive lymphocytosis in prolymphocytic leukemia.

Leukemia & lymphoma - 1 Apr 1998

Weston K M, Mulligan S P, Raison R L

Abstract excerpt

Surface IgM expressed by malignant CD5+ B-cells from patients with B-chronic lymphocytic leukemia (B-CLL) has previously been shown to bind mouse Ig in what appears to be an example of polyreactive antigen-binding activity. This report demonstrates the in vitro and in vivo binding of mouse Ig to...

Topics

Animals
Antibodies, Monoclonal
Humans
Immunoglobulin G
Leukemia, B-Cell
Leukemia, Prolymphocytic
Lymphocytosis
Male
Mice
Middle Aged
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9684933
DOI: 10.3109/10428199809068572

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9684933-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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