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Twist is required for establishment of the mouse coronal suture

27 Apr 2005

Abstract excerpt

Cranial sutures are the growth centres of the skull, enabling expansion of the skull to accommodate rapid growth of the brain. Haploinsufficiency of the human TWIST gene function causes the craniosynostosis syndrome, Saethre-Chotzen syndrome (SCS), in which premature fusion of the coronal suture is a characteristic feature. Previous studies have indicated that Twist is expressed in the coronal suture during...

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PMID: 15857364
DOI: 10.1111/j.1469-7580.2005.00411.x

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