Article
Cell mixing at a neural crest-mesoderm boundary and deficient ephrin-Eph signaling in the pathogenesis of craniosynostosis.
Human molecular genetics - 15 Apr 2006
Merrill Amy E, Bochukova Elena G, Brugger Sean M, Ishii Mamoru, Pilz Daniela T, Wall Steven A, Lyons Karen M, Wilkie Andrew O M, Maxson Robert E
Abstract excerpt
Boundaries between cellular compartments often serve as signaling interfaces during embryogenesis. The coronal suture is a major growth center of the skull vault and develops at a boundary between cells derived from neural crest and mesodermal origin, forming the frontal and parietal bones, respectively. Premature fusion of these bones, termed coronal synostosis, is a common human developmental anomaly. Known...
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