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Article

Genetic and biochemical characterization of the E32del polymorphism in human mesotrypsinogen.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Jan 2005

Nemoda Zsófia, Teich Niels, Hugenberg Christin, Sahin-Tóth Miklós

Abstract excerpt

BACKGROUND/AIMS: Mesotrypsin is a minor pancreatic digestive enzyme that degrades dietary trypsin inhibitors in the gut. In this study, we tested the hypothesis that the E32del genetic variant of mesotrypsin might represent a risk factor for the development of chronic pancreatitis, as a result of enhanced degradation of pancreatic secretory trypsin inhibitor. METHODS: We screened 97 German patients with chronic...

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Identifiers

PMID: 15855826
DOI: 10.1159/000085282
PMCID: PMC1401494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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