Article
Knockdown of the Plasmodium falciparum SURFIN4.1 antigen leads to an increase of its cognate transcript.
PloS one - 1 Jan 2017
Macedo-Silva Tatiane, Araujo Rosana Beatriz Duque, Meissner Kamila Anna, Fotoran Wesley Luzetti, Medeiros Márcia Melo, de Azevedo Mauro Ferreira, Wunderlich Gerhard
Abstract excerpt
The genome of the malaria parasite Plasmodium falciparum contains the surf gene family which encodes large transmembrane proteins of unknown function. While some surf alleles appear to be expressed in sexual stages, others occur in asexual blood stage forms and may be associated to virulence-associated processes and undergo transcriptional switching. We accessed the transcription of surf genes along multiple...
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