Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Abnormal cardiac inflow patterns during postnatal development in a mouse model of Holt-Oram syndrome.

American journal of physiology. Heart and circulatory physiology - 1 Sept 2005

Zhou Yu-Qing, Zhu Yonghong, Bishop Jonathan, Davidson Lorinda, Henkelman R Mark, Bruneau Benoit G, Foster F Stuart

Abstract excerpt

Tbx5(del/+) mice provide a model of human Holt-Oram syndrome. In this study, the cardiac functional phenotypes of this mouse model were investigated with 30-MHz ultrasound by comparing 12 Tbx5(del/+) mice with 12 wild-type littermates at 1, 2, 4, and 8 wk of age. Cardiac dimensions were measured...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diastole
Share to Echocardiography
Share to Heart

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Defects, Congenital

Share to Heart Septal Defects, Atrial

Share to Systole

Share to T-Box Domain Proteins

Share to Ventricular Dysfunction, Left

Source

Identifiers

PMID: 15849237
DOI: 10.1152/ajpheart.00027.2005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15849237-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Abnormal cardiac inflow patterns during postnatal development in a mouse model of Holt-Oram syndrome.PMID 15849237Read ↗

The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction systemSemantic proximity Read ↗

A Murine Model of Holt-Oram Syndrome Defines Roles of the T-Box Transcription Factor Tbx5 in Cardiogenesis and DiseaseSemantic proximity Read ↗

Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome.Semantic proximity Read ↗

Clinical and molecular characterisation of Holt-Oram syndrome focusing on cardiac manifestations.Semantic proximity Read ↗

Tbx5-dependent pathway regulating diastolic function in congenital heart diseaseSemantic proximity Read ↗

Current advances in Holt-Oram syndrome.Semantic proximity Read ↗

Progressive troponin I loss impairs cardiac relaxation and causes heart failure in mice.Semantic proximity Read ↗

Developmental paradigms in heart disease: insights from tinman.Semantic proximity Read ↗

Microarray analysis of Tbx5-induced genes expressed in the developing heart.Semantic proximity Read ↗

Identification and localization of TBX5 transcription factor during human cardiac morphogenesisSemantic proximity Read ↗

Characterization of Cardiac Conduction System Abnormalities in Mice with Targeted Disruption of Six5 GeneSemantic proximity Read ↗

Coordinated <i>Tbx3/Tbx5</i> transcriptional control of the adult ventricular conduction systemSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.