Article
Microarray analysis of Tbx5-induced genes expressed in the developing heart.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 2006
Plageman Timothy F, Yutzey Katherine E
Abstract excerpt
Tbx5 is a member of the T-box family of transcription factors and is associated with Holt-Oram syndrome (HOS), a congenital disorder characterized by heart and limb defects. Although implicated in several processes during development, only a few genes regulated by Tbx5 have been reported. To identify candidate genes regulated by Tbx5 during heart development, a microarray approach was used. A cardiac-derived...
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