Article
Genetic variation and brain gene expression in rodent models of alcoholism implications for medication development.
International review of neurobiology - 1 Jan 2010
Björk Karl, Hansson Anita C, Sommer Wolfgang H
Abstract excerpt
Much research on experimental animals that is aimed to decipher genetic factors involved in alcoholism has been devoted to either models of innate alcohol-related phenotypes or responses after acute alcohol challenge. Such focus has, however, limitations when it comes to the pathogenetic mechanism underlying alcohol addiction, because the progression into the disorder takes years and genetic as well as...
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