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Article

Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network.

eLife - 25 May 2023

Letelier Joaquín, Buono Lorena, Almuedo-Castillo María, Zang Jingjing, Mounieres Constanza, González-Díaz Sergio, Polvillo Rocío, Sanabria-Reinoso Estefanía, Corbacho Jorge, Sousa-Ortega Ana, Diez Del Corral Ruth, Neuhauss Stephan C F, Martínez-Morales Juan R

Abstract excerpt

Genetic studies in human and mice have established a dual role for Vsx genes in retina development: an early function in progenitors' specification, and a later requirement for bipolar-cells fate determination. Despite their conserved expression patterns, it is currently unclear to which extent Vsx functions are also conserved across vertebrates, as mutant models are available only in mammals. To gain insight...

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Identifiers

PMID: 37227126
DOI: 10.7554/eLife.85594
PMCID: PMC10212559

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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