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Article

RNA-Binding Protein RBM24 Regulates p63 Expression via mRNA Stability

28 Dec 2013

Abstract excerpt

UNLABELLED: p63, a p53 family member, plays pivotal roles in epidermal development, aging, and tumorigenesis. Thus, understanding how p63 expression is controlled has biological and clinical importance. RBM24 is an RNA-binding protein and shares a high sequence similarity with RBM38, a critical regulator of p63. In this study, we investigated whether RBM24 is capable of regulating p63 expression. Indeed, we found...

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PMID: 24375645
DOI: 10.1158/1541-7786.mcr-13-0526

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