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Article

Association of soluble epoxide hydrolase gene polymorphism with insulin resistance in type 2 diabetic patients.

Biochemical and biophysical research communications - 27 May 2005

Ohtoshi Kentaro, Kaneto Hideaki, Node Koichi, Nakamura Yumiko, Shiraiwa Toshihiko, Matsuhisa Munehide, Yamasaki Yoshimitsu

Abstract excerpt

The insulin resistance found in diabetes is influenced by vascular tone and local blood flow. Endothelial-derived hyperpolarizing factor (EDHF) functions as a potent vasodilator to regulate vascular tone, and its production is regulated by soluble epoxide hydrolase (sEH). In this study, we examined the genotype distribution and allele frequency of sEH gene G860A (Arg287Gln) polymorphism in Japanese subjects...

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Share to Amino Acid Substitution
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epoxide Hydrolases

Share to Gene Frequency

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Genetic

Source

Identifiers

PMID: 15845398
DOI: 10.1016/j.bbrc.2005.03.171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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