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Article

Luman is capable of binding and activating transcription from the unfolded protein response element.

Biochemical and biophysical research communications - 27 May 2005

DenBoer Lisa M, Hardy-Smith Philip W, Hogan Melissa R, Cockram Gregory P, Audas Timothy E, Lu Rui

Abstract excerpt

Luman (or LZIP, CREB3) is a transcription factor with an endoplasmic reticulum (ER)-transmembrane domain. Due to its structural similarities with ATF6, it is thought that Luman might also be involved in cellular stress responses. Here we report that Luman can bind and activate transcription from the consensus unfolded protein response element (UPRE). Mutations that disrupted the binding of Luman to the UPREs...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15845366
DOI: 10.1016/j.bbrc.2005.03.141

Genes

ATF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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