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Article

Cryptic promoter activity in the DNA sequence corresponding to the pim-1 5'-UTR

11 Apr 2005

Abstract excerpt

The serine/threonine kinase pim-1 mRNA contains a long and G/C rich 5'-untranslated region (5'-UTR). Previous work suggested that the pim-1 5'-UTR harbors an internal ribosomal entry site (IRES) allowing for internal initiation of translation. However, several previously reported eukaryotic IRES elements actually contain cryptic promoter activity. To test whether an IRES or a cryptic promoter is present in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15843687
DOI: 10.1093/nar/gki523

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