Article
crossveinless-c is a RhoGAP required for actin reorganisation during morphogenesis.
Development (Cambridge, England) - 1 May 2005
Denholm Barry, Brown Stephen, Ray Robert P, Ruiz-Gómez Mar, Skaer Helen, Hombría James Castelli-Gair
Abstract excerpt
Members of the Rho family of small GTPases are required for many of the morphogenetic processes required to shape the animal body. The activity of this family is regulated in part by a class of proteins known as RhoGTPase Activating Proteins (RhoGAPs) that catalyse the conversion of RhoGTPases to their inactive state. In our search for genes that regulate Drosophila morphogenesis, we have isolated several lethal...
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