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Article

Pre-steady-state kinetic analysis of riboflavin synthase using a pentacyclic reaction intermediate as substrate.

Biological chemistry - 1 Feb 2005

Illarionov Boris, Haase Ilka, Fischer Markus, Bacher Adelbert, Schramek Nicholas

Abstract excerpt

Riboflavin synthase catalyses a mechanistically complex dismutation affording riboflavin and 5-amino-6-ribitylamino-2,4(1H,3H )-pyrimidinedione from 6,7-dimethyl-8-ribityllumazine. A pentacyclic adduct (compound 2 ) of two substrate molecules was used as substrate for pre-steady-state kinetic analysis. Whereas the wild-type enzyme catalyses the decomposition of compound 2 into a mixture of riboflavin and...

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PMID: 15843156
DOI: 10.1515/BC.2005.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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