Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experiments.

BMC biochemistry - 23 Dec 2003

Fischer Markus, Schott Ann-Kathrin, Kemter Kristina, Feicht Richard, Richter Gerald, Illarionov Boris, Eisenreich Wolfgang, Gerhardt Stefan, Cushman Mark, Steinbacher Stefan, Huber Robert, Bacher Adelbert

Abstract excerpt

BACKGROUND: Riboflavin synthase catalyzes the transformation of 6,7-dimethyl-8-ribityllumazine into riboflavin in the last step of the riboflavin biosynthetic pathway. Gram-negative bacteria and certain yeasts are unable to incorporate riboflavin from the environment and are therefore absolutely dependent on endogenous synthesis of the vitamin. Riboflavin synthase is therefore a potential target for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Molecular Sequence Data

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Nuclear Magnetic Resonance, Biomolecular

Share to Pteridines

Share to Riboflavin

Share to Schizosaccharomyces

Share to Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 14690539
DOI: 10.1186/1471-2091-4-18
PMCID: PMC337094

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experiments.PMID 14690539Read ↗

The Saccharomyces cerevisiae RIB4 gene codes for 6,7-dimethyl-8-ribityllumazine synthase involved in riboflavin biosynthesis. Molecular characterization of the gene and purification of the encoded protein.Semantic proximity Read ↗

Structural basis of charge transfer complex formation by riboflavin bound to 6,7-dimethyl-8-ribityllumazine synthase.Semantic proximity Read ↗

Complex structure of Bacillus subtilis RibG: the reduction mechanism during riboflavin biosynthesis.Semantic proximity Read ↗

Riboflavin biosynthesis in Saccharomyces cerevisiae. Cloning, characterization, and expression of the RIB5 gene encoding riboflavin synthase.Semantic proximity Read ↗

Identification of riboflavin: revealing different metabolic characteristics between Escherichia coli BL21(DE3) and MG1655.Semantic proximity Read ↗

Biosynthesis of riboflavin. Screening for an improved GTP cyclohydrolase II mutant.Semantic proximity Read ↗

Validation and Development of an Escherichia coli Riboflavin Pathway Phenotypic Screen Hit as a Small-Molecule Ligand of the Flavin Mononucleotide Riboswitch.Semantic proximity Read ↗

Pre-steady-state kinetic analysis of riboflavin synthase using a pentacyclic reaction intermediate as substrate.Semantic proximity Read ↗

Site-specific incorporation of 5-fluorotryptophan as a probe of the structure and function of the membrane-bound D-lactate dehydrogenase of Escherichia coli: a 19F nuclear magnetic resonance study.Semantic proximity Read ↗

The monocarboxylate transporter homolog Mch5p catalyzes riboflavin (vitamin B2) uptake in Saccharomyces cerevisiae.Semantic proximity Read ↗

Impact of natural mutations on the riboflavin transporter 2 and their relevance to human riboflavin transporter deficiency 2.Semantic proximity Read ↗

Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.