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Article

Truncation of the projection domain of MAP4 (microtubule-associated protein 4) leads to attenuation of microtubule dynamic instability.

Cell structure and function - 1 Feb 2005

Permana Sofy, Hisanaga Shin-ichi, Nagatomo Yoko, Iida Junko, Hotani Hirokazu, Itoh Tomohiko J

Abstract excerpt

MAP4, a ubiquitous heat-stable MAP, is composed of an asymmetric structure common to the heat-stable MAPs, consisting of an N-terminal projection (PJ) domain and a C-terminal microtubule (MT)-binding (MTB) domain. Although the MTB domain has been intensively studied, the role of the PJ domain, which protrudes from MT-wall and does not bind to MTs, remains unclear. We investigated the roles of the PJ domain on the...

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Source

Identifiers

PMID: 15840946
DOI: 10.1247/csf.29.147

Genes

MAP4
MAP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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