Article
miR-58 family and TGF-β pathways regulate each other in Caenorhabditis elegans.
Nucleic acids research - 16 Nov 2015
de Lucas María Pilar, Sáez Alberto G, Lozano Encarnación
Abstract excerpt
Despite the fact that microRNAs (miRNAs) modulate the expression of around 60% of protein-coding genes, it is often hard to elucidate their precise role and target genes. Studying miRNA families as opposed to single miRNAs alone increases our chances of observing not only mutant phenotypes but also changes in the expression of target genes. Here we ask whether the TGF-β signalling pathways, which control many...
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