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Article

Epigenetic regulation in mammalian preimplantation embryo development

5 Jun 2009

Abstract excerpt

Preimplantation embryo development involves four stages: fertilization, cell cleavage, morula and blastocyst formation. During these stages, maternal and zygotic epigenetic factors play crucial roles. The gene expression profile is changed dramatically, chromatin is modified and core histone elements undergo significant changes. Each preimplantation embryo stage has its own characteristic epigenetic profile,...

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PMID: 19500360
DOI: 10.1186/1477-7827-7-59

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