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Article

Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population.

Molecular psychiatry - 1 Jul 2005

Thomson P A, Wray N R, Millar J K, Evans K L, Hellard S Le, Condie A, Muir W J, Blackwood D H R, Porteous D J

Abstract excerpt

The Translin-associated factor X/Disrupted in Schizophrenia 1 (TRAX/DISC) region was first implicated as a susceptibility locus for schizophrenia by analysis of a large Scottish family in which a t(1;11) translocation cosegregates with schizophrenia, bipolar disorder and recurrent major depression. We now report evidence for association between bipolar disorder and schizophrenia and this locus in the general...

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Source

Identifiers

PMID: 15838535
DOI: 10.1038/sj.mp.4001669

Genes

DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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