Article
Somatic mutations of EGFR gene in squamous cell carcinoma of the head and neck.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2005
Lee Jong Woo, Soung Young Hwa, Kim Su Young, Nam Hyo Kyung, Park Won Sang, Nam Suk Woo, Kim Min Sik, Sun Dong Il, Lee Youn Soo, Jang Ja June, Lee Jung Young, Yoo Nam Jin, Lee Sug Hyung
Abstract excerpt
PURPOSE: Recently, the kinase domain mutations of epidermal growth factor receptor (EGFR) gene have been identified in non-small-cell lung cancer, and these mutations have been related to the clinical response to the tyrosine kinase inhibitor gefitinib. Gefitinib treatment has also shown clinical benefits in squamous cell carcinoma of the head and neck (SCCHN). The aim of this study was to explore the possibility...
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