Article
A screen for genes regulating the wingless gradient in Drosophila embryos.
Genetics - 1 Jun 2005
Desbordes Sabrina C, Chandraratna Dhianjali, Sanson Bénédicte
Abstract excerpt
During the development of the Drosophila embryonic epidermis, the secreted Wingless protein initially spreads symmetrically from its source. At later stages, Wingless becomes asymmetrically distributed in a Hedgehog-dependent manner, to control the patterning of the embryonic epidermis. When Wingless is misexpressed in engrailed cells in hedgehog heterozygous mutant embryos, larvae show a dominant phenotype...
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