Article
Common variants of the endothelial nitric oxide synthase gene and the risk of coronary heart disease among U.S. diabetic men.
Diabetes - 1 Jul 2006
Zhang Cuilin, Lopez-Ridaura Ruy, Hunter David J, Rifai Nader, Hu Frank B
Abstract excerpt
Endothelial nitric oxide synthase (eNOS) gene represents a promising candidate gene for coronary heart disease (CHD) because of its impact on eNOS activity. We systematically examined the associations of eight variants of the eNOS gene (two potentially functional variants [-786T>C and Glu298Asp] and six tagging single nucleotide polymorphisms) with CHD risk in a large cohort of diabetic patients. Among 861...
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