Article
EGFR mutation is specific for terminal respiratory unit type adenocarcinoma.
The American journal of surgical pathology - 1 May 2005
Yatabe Yasushi, Kosaka Takayuki, Takahashi Takashi, Mitsudomi Tetsuya
Abstract excerpt
We have previously reported that terminal-respiratory-unit (TRU) type adenocarcinoma is a distinct subset of lung adenocarcinoma in terms of molecular pathway for carcinogenesis and phenotypic profiles. This type of cancer shows TRU features, characterized by distinct cellular morphology and the expression of TTF-1 and surfactant proteins. Recently, two groups published novel mutations of the epidermal growth...
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