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Article

Expression profile-defined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Apr 2006

Takeuchi Toshiyuki, Tomida Shuta, Yatabe Yasushi, Kosaka Takayuki, Osada Hirotaka, Yanagisawa Kiyoshi, Mitsudomi Tetsuya, Takahashi Takashi

Abstract excerpt

PURPOSE: This study was conducted to gain insight into the relationship between expression profiles and underlying genetic changes, which are known to be important for the pathogenesis of lung cancers. METHODS: Expression profiles of 18,175 unique genes and three major targets for genetic changes, p53, epidermal growth factor receptor (EGFR), and K-ras, were investigated in 149 patients with non-small-cell lung...

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Identifiers

PMID: 16549822
DOI: 10.1200/JCO.2005.03.8224

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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