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Article

Terminal respiratory unit type lung adenocarcinoma is associated with distinctive EGFR immunoreactivity and EGFR mutations.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Sept 2007

Peterson Michael R, Piao Zhe, Bazhenova Lyudmila A, Weidner Noel, Yi Eunhee S

Abstract excerpt

Approximately 10% to 20% of nonsmall cell lung cancer patients respond to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors, such as gefitinib. Responders are mostly nonsmokers and women with tumors displaying bronchioloalveolar features. Mutations of the tyrosine kinase domain of the EGFR gene have been associated with a clinical response to gefitinib. A recent study reported that the terminal...

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Source

Identifiers

PMID: 17721266
DOI: 10.1097/PAI.0b013e31802d1590

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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