Article
EGFR mutations and the terminal respiratory unit.
Cancer metastasis reviews - 1 Mar 2010
Yatabe Yasushi
Abstract excerpt
Considerable knowledge has accumulated about mutations of the epidermal growth factor receptor (EGFR)-tyrosine kinase domain since these were first identified in 2004. Patients with nonsmall cell lung cancer with this mutation show dramatic clinical responses to treatment with EGFR-tyrosine kinas...
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