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Article

SPBP is a phosphoserine-specific repressor of estrogen receptor alpha.

Molecular and cellular biology - 1 May 2005

Gburcik Valentina, Bot Nathalie, Maggiolini Marcello, Picard Didier

Abstract excerpt

Multiple signaling pathways stimulate the activity of estrogen receptor alpha (ERalpha) by direct phosphorylation within its N-terminal activation function 1 (AF1). How phosphorylation affects AF1 activity remains poorly understood. We performed a phage display screen for human proteins that are exclusively recruited to the phosphorylated form of AF1 and found the stromelysin-1 platelet-derived growth...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15831449
DOI: 10.1128/MCB.25.9.3421-3430.2005
PMCID: PMC1084313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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