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Polybrominated diphenyl ethers BDE-47 and BDE-99 modulate murine melanoma cell phenotype in vitro.

Environmental science and pollution research international - 1 Feb 2022

Steil Gisleine Jarenko, Buzzo João Luiz Aldinucci, de Oliveira Ribeiro Ciro Alberto, Filipak Neto Francisco

Abstract excerpt

Cancer is one of the leading causes of mortality worldwide. Even with the advances of pharmaceutical industry and treatments, the mortality rate for various types of cancer remains high. In particular, phenotypic alterations of tumor cells concerning drug efflux, migratory and invasive capabilities may represent a hurdle for cancer treatment and contribute to poor prognosis. In the present study, we investigated...

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PMID: 34535858
DOI: 10.1007/s11356-021-16455-0

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