Article
A single nucleotide polymorphism based approach for the identification and characterization of gene expression modulation using MassARRAY.
Mutation research - 3 Jun 2005
Jurinke Christian, Denissenko Mikhail F, Oeth Paul, Ehrich Matthias, van den Boom Dirk, Cantor Charles R
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are the most common form of genetic variation. Their abundance and the ease with which they can be assayed have lead to their use in applications beyond simple genotyping. One such application is the quantitative determination of transcript levels associated with distinct alleles or haplotypes found in promoters and coding regions of genes. These changes in expression due to...
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