Article
The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis.
Developmental biology - 15 May 1998
Thompson M A, Ransom D G, Pratt S J, MacLennan H, Kieran M W, Detrich H W, Vail B, Huber T L, Paw B, Brownlie A J, Oates A C, Fritz A, Gates M A, Amores A, Bahary N, Talbot W S, Her H, Beier D R, Postlethwait J H, Zon L I
Abstract excerpt
In vertebrates, hematopoietic and vascular progenitors develop from ventral mesoderm. The first primitive wave of hematopoiesis yields embryonic red blood cells, whereas progenitor cells of subsequent definitive waves form all hematopoietic cell lineages. In this report we examine the development of hematopoietic and vasculogenic cells in normal zebrafish and characterize defects in cloche and spadetail mutant...
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