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Association of IFN-gamma and IL-10 gene variants with the risk of extrapulmonary tuberculosis

17 Jun 2021

Abstract excerpt

Tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) is a chronic infectious disease. Interferon-gamma (IFN-γ) is an important cytokine imparting resistance to mycobacterial diseases. It is believed that IFN-γ and Interleukin-10 (IL-10) play divergent roles in the host immune system against MTB infection. IL-10 is an important inhibitory cytokine and helps balancing the inflammatory and immune responses....

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PMID: 34354401
DOI: 10.1016/j.sjbs.2021.06.029

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