Article
The number of lymph node metastases in gastric cancer correlates with the angiotensin I-converting enzyme gene insertion/deletion polymorphism.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2005
Röcken Christoph, Lendeckel Uwe, Dierkes Jutta, Westphal Sabine, Carl-McGrath Stacy, Peters Brigitte, Krüger Sabine, Malfertheiner Peter, Roessner Albert, Ebert Matthias P A
Abstract excerpt
PURPOSE: In the present study, we aimed to substantiate the putative significance of angiotensin I-converting enzyme (ACE) on gastric cancer biology by investigating the influence of its gene polymorphism on gastric cancer progression. EXPERIMENTAL DESIGN: Genomic DNA was purified from peripheral blood mononuclear cells or tissue specimens. Amplified ACE gene fragments were separated on agarose gels. D or I...
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