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Article

The gene polymorphism of the angiotensin I-converting enzyme correlates with tumor size and patient survival in colorectal cancer patients.

Neoplasia (New York, N.Y.) - 1 Sept 2007

Röcken Christoph, Neumann Konrad, Carl-McGrath Stacy, Lage Hermann, Ebert Matthias P A, Dierkes Jutta, Jacobi Christoph A, Kalmuk Sinan, Neuhaus Peter, Neumann Ulf

Abstract excerpt

We studied the putative significance of angiotensin I-converting enzyme (ACE) in colorectal cancer (CRC) biology. Local expression of ACE was investigated by quantitative reverse transcription-polymerase chain reaction and by immunohistochemistry in CRCs and adenomas. ACE insertion (I)/deletion (D) polymorphism was studied in 141 CRC patients and 189 controls. ACE mRNA was upregulated in CRCs compared to...

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Identifiers

PMID: 17898867
DOI: 10.1593/neo.07418
PMCID: PMC1993856

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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