Article
No association between angiotensin I converting enzyme (ACE) I/D polymorphism and gastric cancer risk among Japanese.
Nagoya journal of medical science - 1 Aug 2011
Hibi Satoshi, Goto Yasuyuki, Ando Takafumi, Matsuo Keitaro, Wakai Kenji, Tajima Kazuo, Goto Hidemi, Hamajima Nobuyuki
Abstract excerpt
The angiotensin I-converting enzyme (ACE) is involved in cell proliferation, angiogenesis, inflammation, and tissue remodeling, all of which could play a role in carcinogenesis. The DD genotype of ACE I/D polymorphism with a higher ACE level than either ID or II genotypes was reported to increase the risk of several cancers. This is a case-control study examining the association between the polymorphism and...
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