Exogenous Alginate Protects Staphylococcus aureus from Killing by Pseudomonas aeruginosa

Abstract excerpt

CF patients are chronically infected by polymicrobial communities. The two dominant bacterial pathogens that infect the lungs of CF patients are P. aeruginosa and S. aureus , with ∼30% of patients coinfected by both species. Such coinfected individuals have worse outcomes than monoinfected patients, and both species persist within the same physical space. A variety of host and environmental factors have been...

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