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Article

The enigma of arsenic carcinogenesis: role of metabolism.

Toxicological sciences : an official journal of the Society of Toxicology - 1 May 1999

Goering P L, Aposhian H V, Mass M J, Cebrián M, Beck B D, Waalkes M P

Abstract excerpt

Inorganic arsenic is considered a high-priority hazard, particularly because of its potential to be a human carcinogen. In exposed human populations, arsenic is associated with tumors of the lung, skin, bladder, and liver. While it is known to be a human carcinogen, carcinogenesis in laboratory animals by this metalloid has never been convincingly demonstrated. Therefore, no animal models exist for studying...

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PMID: 10367337
DOI: 10.1093/toxsci/49.1.5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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