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Article

Distinct molecular phenotype of malignant CD34(+) hematopoietic stem and progenitor cells in chronic myelogenous leukemia.

Oncogene - 11 Aug 2005

Kronenwett Ralf, Butterweck Ulf, Steidl Ulrich, Kliszewski Slawomir, Neumann Frank, Bork Simone, Blanco Elena Diaz, Roes Nicole, Gräf Thorsten, Brors Benedikt, Eils Roland, Maercker Christian, Kobbe Guido, Gattermann Norbert, Haas Rainer

Abstract excerpt

Chronic myelogenous leukemia (CML) is a malignant disorder of the hematopoietic stem cell characterized by the BCR-ABL oncogene. We examined gene expression profiles of highly enriched CD34(+) hematopoietic stem and progenitor cells from patients with CML in chronic phase using cDNA arrays covering 1.185 genes. Comparing CML CD34(+) cells with normal CD34(+) cells, we found 158 genes which were significantly...

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Share to Antigens, CD34
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

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Source

Identifiers

PMID: 15806158
DOI: 10.1038/sj.onc.1208596

Genes

BCR
SKI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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