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Article

Bayesian coestimation of phylogeny and sequence alignment.

BMC bioinformatics - 1 Apr 2005

Lunter Gerton, Miklós István, Drummond Alexei, Jensen Jens Ledet, Hein Jotun

Abstract excerpt

BACKGROUND: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this problem is to first build a multiple alignment of these sequences, followed by a phylogenetic reconstruction step based on this multiple alignment. However, alignment and phylogenetic inference are fundamentally interdependent, and...

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PMID: 15804354
DOI: 10.1186/1471-2105-6-83
PMCID: PMC1087833

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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