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Article

Phosphodiesterase 4D gene, ischemic stroke, and asymptomatic carotid atherosclerosis.

Stroke - 1 May 2005

Bevan S, Porteous L, Sitzer M, Markus H S

Abstract excerpt

BACKGROUND AND PURPOSE: Phosphodiesterase 4D (PDE4D) was identified recently as the first novel stroke gene to predispose to ischemic stroke independently of conventional risk factors. An association was only found with large vessel and cardioembolic stroke, suggesting a mechanism of accelerated atherosclerosis. We sought to replicate this association in ischemic stroke as a whole, and individual stroke subtypes,...

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Source

Identifiers

PMID: 15802632
DOI: 10.1161/01.STR.0000162713.06519.41

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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