Article
Confirmation of linkage to ocular refraction on chromosome 22q and identification of a novel linkage region on 1q.
Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Jan 2007
Klein Alison P, Duggal Priya, Lee Kristine E, Klein Ronald, Bailey-Wilson Joan E, Klein Barbara E K
Abstract excerpt
OBJECTIVE: To localize genes influencing ocular refraction in subjects in the Beaver Dam Eye Study. Previous studies establish that myopia clusters within families and linkage to myopia has been demonstrated on 2q, 4q, 12q, 17q, 18q, 22q, and Xq. Few studies have examined genetic effects across the entire range of refraction, though linkages to 1p, 3q, 4q, 8p, and 11p have been reported, and our previous analysis...
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