Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Srs2 and RecQ homologs cooperate in mei-3-mediated homologous recombination repair of Neurospora crassa.

Nucleic acids research - 1 Jan 2005

Suzuki Keiichiro, Kato Akihiro, Sakuraba Yoshiyuki, Inoue Hirokazu

Abstract excerpt

Homologous recombination and post-replication repair facilitate restart of stalled or collapsed replication forks. The SRS2 gene of Saccharomyces cerevisiae encodes a 3'-5' DNA helicase that functions both in homologous recombination repair and in post-replication repair. This study identifies and characterizes the SRS2 homolog in Neurospora crassa, which we call mus-50. A knockout mutant of N.crassa, mus-50, is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Helicases
Share to DNA Repair
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fungal Proteins

Share to Genes, Lethal

Share to Methyl Methanesulfonate

Share to Neurospora crassa

Share to Suppression, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 15800214
DOI: 10.1093/nar/gki326
PMCID: PMC1072801

Genes

RAD51
RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Srs2 and RecQ homologs cooperate in mei-3-mediated homologous recombination repair of Neurospora crassa.PMID 15800214Read ↗

Srs2 and Mus81-Mms4 Prevent Accumulation of Toxic Inter-Homolog Recombination Intermediates.Semantic proximity Read ↗

Growth defect and mutator phenotypes of RecQ-deficient Neurospora crassa mutants separately result from homologous recombination and nonhomologous end joining during repair of DNA double-strand breaks.Semantic proximity Read ↗

Requirement of Rrm3 helicase for repair of spontaneous DNA lesions in cells lacking Srs2 or Sgs1 helicase.Semantic proximity Read ↗

The srs2 suppressor of UV sensitivity acts specifically on the RAD5- and MMS2-dependent branch of the RAD6 pathway.Semantic proximity Read ↗

Mus81, Rhp51(Rad51), and Rqh1 form an epistatic pathway required for the S-phase DNA damage checkpoint.Semantic proximity Read ↗

Saccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activities.Semantic proximity Read ↗

Involvement of Schizosaccharomyces pombe Srs2 in cellular responses to DNA damage.Semantic proximity Read ↗

Mutations in recombinational repair and in checkpoint control genes suppress the lethal combination of srs2Delta with other DNA repair genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

Rad51 determines pathway usage in post-replication repair.Semantic proximity Read ↗

Mus81 is essential for sister chromatid recombination at broken replication forks.Semantic proximity Read ↗

Remodeling of the Rad51 DNA strand-exchange protein by the Srs2 helicase.Semantic proximity Read ↗

Genetic and molecular characterization of Neurospora crassa mus-23: a gene involved in recombinational repair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.