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BRCA1 and pancreatic cancer: pedigree findings and their causal relationships.

Cancer genetics and cytogenetics - 15 Apr 2005

Lynch Henry T, Deters Carolyn A, Snyder Carrie L, Lynch Jane F, Villeneuve Pierre, Silberstein Julie, Martin Holly, Narod Steven A, Brand Randall E

Abstract excerpt

Anecdotal reports and series studies indicate that 5-10% of pancreatic cancer (PC) cases are familial. In addition, PC is associated with a variety of hereditary cancer syndromes. PC appears to be an integral cancer in the hereditary breast-ovarian cancer (HBOC) syndrome, with most notice given to the role of BRCA2. Our purpose is to call attention to BRCA1, which also predisposes to PC. Using data from our...

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Identifiers

PMID: 15796958
DOI: 10.1016/j.cancergencyto.2004.01.032

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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